Fig. 5From: Genetic interaction between RLM1 and F-box motif encoding gene SAF1 contributes to stress response in Saccharomyces cerevisiaeSAF1 and RLM1 both require cellular growth response to genotoxic and microtubule depolymerizing agents. A, B, C, D Comparative cellular growth response of cells of WT, saf1∆, rlm1∆, saf1∆rlm1∆ strains in presence of 0.035% MMS, 200 mM HU, 50 μg/ml Nocodazole and 100 μg/ml benomyl by spot assay. The cells lacking SAF1 and RLM1 together show sensitivity to HU, Nocodazole and Benomyl compared to WT however, similar growth profile to WT in case of growth on plates with MMS. E Comparative morphology of cells of WT, saf1∆, rlm1∆, and saf1∆rlm1∆ strains grown on YPD + agar media alone and media with HU and Nocodazole stress agents. Cells grown on genotoxic agents show altered cell divisionBack to article page