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Table 3 Relationships between clinical characteristics and DNA adducts by tissue types

From: A DNA adductome analysis revealed a reduction in the global level of C5-hydroxymethyl-2′-deoxycytidine in the non-tumoral upper urinary tract mucosa of urothelial carcinoma patients

  5mdC 5hmdC 5fdC dI 8-OHdA 8-OHdG
Renal cortex (n = 26)
 Sex (Male vs Female) 0.40 0.26 1.00 0.46 0.50 0.57
 Smoking history (+) vs (−)* 0.77 0.39 1.00 0.97 0.50 0.86
 Taking herbs (Yes vs No) 0.041 0.005 NA 0.44 1.00 NA
 RCC (present vs absent) 0.18 0.82 0.80 0.23 0.33 1.00
Renal medulla (n = 21)
 Sex (Male vs Female) 0.70 0.64 NA 0.57 NA NA
 Smoking history (+) vs (−) 0.10 0.43 NA 0.085 1.00 0.20
 Taking herbs (Yes vs No) NA NA NA NA NA NA
 RCC (present vs absent) 0.51 1.00 1.00 0.70 1.00 0.40
Renal pelvis (n = 25)
 Sex (Male vs Female) 0.60 0.98 1.00 0.44 NA 0.84
 Smoking history (+) vs (−) 0.73 0.69 0.40 1.00 NA 0.11
 Taking herbs (Yes vs No)** 0.087 0.18 0.88 0.80 NA 0.44
 UTUC (present vs absent) 0.08 0.010 1.00 0.89 0.67 0.38