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Table 3 Relationships between clinical characteristics and DNA adducts by tissue types

From: A DNA adductome analysis revealed a reduction in the global level of C5-hydroxymethyl-2′-deoxycytidine in the non-tumoral upper urinary tract mucosa of urothelial carcinoma patients

 

5mdC

5hmdC

5fdC

dI

8-OHdA

8-OHdG

Renal cortex (n = 26)

 Sex (Male vs Female)

0.40

0.26

1.00

0.46

0.50

0.57

 Smoking history (+) vs (−)*

0.77

0.39

1.00

0.97

0.50

0.86

 Taking herbs (Yes vs No)

0.041

0.005

NA

0.44

1.00

NA

 RCC (present vs absent)

0.18

0.82

0.80

0.23

0.33

1.00

Renal medulla (n = 21)

 Sex (Male vs Female)

0.70

0.64

NA

0.57

NA

NA

 Smoking history (+) vs (−)

0.10

0.43

NA

0.085

1.00

0.20

 Taking herbs (Yes vs No)

NA

NA

NA

NA

NA

NA

 RCC (present vs absent)

0.51

1.00

1.00

0.70

1.00

0.40

Renal pelvis (n = 25)

 Sex (Male vs Female)

0.60

0.98

1.00

0.44

NA

0.84

 Smoking history (+) vs (−)

0.73

0.69

0.40

1.00

NA

0.11

 Taking herbs (Yes vs No)**

0.087

0.18

0.88

0.80

NA

0.44

 UTUC (present vs absent)

0.08

0.010

1.00

0.89

0.67

0.38