Skip to main content
Fig. 7 | Genes and Environment

Fig. 7

From: Glycoprotein 2 in health and disease: lifting the veil

Fig. 7

Functional roles of GP2. While the functions of GP2 remain poorly understood, emerging evidence suggests that it plays an antibacterial role in the gastrointestinal tract after being secreted from pancreatic acinar cells. Increasing evidence suggests that GP2 is a key factor in the intestine-pancreas axis, exerting antimicrobial effects in the gastrointestinal tract after being secreted from pancreatic acinar cells. In addition, previous studies have suggested that GP2 may be involved in the pathogenesis of pancreatitis, IBD (CD, UC), and pancreatic adenocarcinoma. Targeting GP2 as well as other genes involved in innate immunity may offer insights into pancreatitis-pancreatic cancer association

Back to article page