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Fig. 6 | Genes and Environment

Fig. 6

From: Reactions of 3′,5′-di-O-acetyl-2′-deoxyguansoine and 3′,5′-di-O-acetyl-2′-deoxyadenosine to UV light in the presence of uric acid

Fig. 6

Uric acid dose-dependence and time-course of the concentration changes of AcdAdo reaction products. Uric acid dose-dependence of the concentration changes of (a) each product and (b) AcdAdo and total products, when a solution of 100 μM AcdAdo with 0–400 μM uric acid was irradiated with UV light through a 300-nm longpass filter for 10 min at pH 7.4 and 37 °C. Time-course of the concentration changes of (c) each product and (d) AcdAdo and total products, when a solution of 100 μM AcdAdo with 400 μM uric acid was irradiated with UV light through a 300-nm longpass filter for 0–30 min at pH 7.4 and 37 °C. Ade (7) (closed circle), Fapy-AcdAdo (8 and 9) (closed triangle), 5′,8-cyclo-AcdAdo (10 and 11) (closed square), 5′-deoxy-5′,8-cyclo-AcdAdo (12) (open circle), 8-oxo-AcdAdo (open triangle), AcdAdo (closed rhombus), total concentration of Products 7–13 (open rhombus). All the reaction mixtures were analyzed by RP-HPLC. Means ± standard deviation (S.D.) (n = 3) are presented

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Genes and Environment

ISSN: 1880-7062

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