Table 1 PM-induced hypomethylation of Alu and LINE1 in NHBE and NHEK
| Â | L1-H | L1-P | L1-M | L1 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | PM 2.5 | PM 10 | PM 10 -PAH | PM 2.5 | PM 10 | PM 10 -PAH | PM 2.5 | PM 10 | PM 10 -PAH | PM 2.5 | PM 10 | PM 10 -PAH |
Unmethylated CpGs in NHBE | 604 | 622 | 702 | 29,409 | 30,050 | 34,696 | 40,765 | 42,033 | 49,037 | 70,778 | 72,706 | 84,603 |
Unmethylated CpGs in NHEK | 591 | 619 | 592 | 20,902 | 22,228 | 20,774 | 24,707 | 26,474 | 27,270 | 46,201 | 49,322 | 48,637 |
Analyzed total CpGs | 43,045 | 1,282,366 | 1,325,962 | 2,651,373 | ||||||||
| Â | Alu Y | Alu S | Alu J | Alu | ||||||||
| Â | PM 2.5 | PM 10 | PM 10 -PAH | PM 2.5 | PM 10 | PM 10 -PAH | PM 2.5 | PM 10 | PM 10 -PAH | PM 2.5 | PM 10 | PM 10 -PAH |
Unmethylated CpGs in NHBE | 28,627 | 26,533 | 28,674 | 92,202 | 85,521 | 99,032 | 17,746 | 17,666 | 19,296 | 138,575 | 129,719 | 144,627 |
Unmethylated CpGs in NHEK | 17,907 | 28,937 | 19,691 | 40,236 | 52,578 | 43,912 | 6,361 | 7,565 | 7,964 | 64,503 | 88,747 | 71,567 |
Analyzed total CpGs | 1,784,717 | 4,454,205 | 801,773 | 7,040,695 | ||||||||