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Fig. 3 | Genes and Environment

Fig. 3

From: Evaluation of a 4-day repeated-dose micronucleus test in rat glandular stomach and colon using aneugens and non-genotoxic non-carcinogens

Fig. 3

Micronucleus test in the glandular stomach, colon, and bone marrow with non-genotoxic non-carcinogens. The test was performed in rats administered NaCl or SUC for 4 days. Each bar represents the frequency of MNed cells or MNed immature erythrocytes (IMEs) (mean ± SD). Each closed circle represents the number of Ki-67 positive cells (per gland or crypt) or %IME (mean ± SD). The horizontal axis represents chemical and/or dosage (mg/kg/day). N, Negative (vehicle) control; P1, positive control (DMH and MNU treatment). Statistical significance: **p < 0.01 (Kastenbaum & Bowman test), ##p < 0.01 (Dunnett’s test), and ††p < 0.01 (Student’s t-test) compared to the negative control

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Genes and Environment

ISSN: 1880-7062

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