Incubation time after removing the compoundsa
|
Cell viability (%)
|
---|
0.5% EtBr
|
0.5% MMS
|
0.001% 4-NQO
|
---|
Non-treated
|
100.0 ± 2.8
|
100.0 ± 2.6
|
100.0 ± 1.5
|
2 h
|
89.3 ± 6.1b
|
115.1 ± 5.1
|
139.2 ± 2.0
|
4 h
|
74.7 ± 8.0b
|
108.1 ± 0.3
|
114.2 ± 14.5
|
6 h
|
73.1 ± 4.6b
|
108.2 ± 4.9
|
122.7 ± 24.2
|
24 h
|
39.1 ± 1.3b
|
108.5 ± 11.3
|
118.3 ± 13.9
|
- Data are presented as the mean ± SD (n = 3)
- EtBr Ethidium bromide, MMS Methyl methanesulfonate, 4-NQO 4-nitroquinoline 1-oxide
- aTime of incubation with fresh culture medium after a 1 min exposure to each compound
- bSignificantly lower than the non-treated group at 5% probability level (Dunnett’s multiple comparison test, one-tailed)