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Fig. 4 | Genes and Environment

Fig. 4

From: MicroRNA miR-627-5p restrains pulmonary artery smooth muscle cell dysfunction by targeting MAP 2 K4 and PI3K/AKT signaling

Fig. 4

The role of the miR-627-5p/MAP2K4 axis in CSE-treated PASMC proliferation and migration. A-B qRT-PCR and western blotting analyses of MAP2K4 expression in PASMCs after indicated transfection. C CCK-8 assay of CSE-treated PASMCs viability after indicated transfection. D The examination of the lactate dehydrogenase (LDH) release of CSE-treated PASMCs after indicated transfection by using an LDH Cytotoxicity Assay Kit. E-F The images of CSE-treated PASMCs after indicated transfection were captured using a light microscopy and cell number was counted with a hemocytometer. G-H Transwell assay of CSE-treated PASMCs migration after indicated transfection. **p<0.01, ***p<0.001

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Genes and Environment

ISSN: 1880-7062

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