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Table 2 TP53 mutation status in Eastern Europe, China, and Japan (exons 4 to 8)

From: Non-CpG sites preference in G:C > A:T transition of TP53 in gastric cancer of Eastern Europe (Poland, Romania and Hungary) compared to East Asian countries (China and Japan)

TP53 mutation

Eastern Europe

China

Japan

P-valuea

P-valueb

n

%

n

%

n

%

Mutant (n = 285, 41.4%)

85

29.5

76

57.1

124

46.3

7 × 10−8

9 × 10−8

Wild type (n = 404, 58.6%)

203

70.5

57

42.9

144

53.7

  
  1. a P-value of the χ2 test for the TP53 mutation prevalence among the three groups: Eastern Europe, China, and Japan
  2. b P-value of the χ2 test for the TP53 mutation prevalence between Eastern Europe and East Asia