Fig. 10From: Mutation and apoptosis are well-coordinated for protecting against DNA damage-inducing toxicity in Drosophila(A) Distribution of mutant spot sizes observed on the wings of larvae (mwh/flr) treated with MNU at 2Â mM (black bars), 6.7Â mM (gray bars), and 0Â mM (white bars). (B) Approximation curves of the spot size fitted by the polynomial approximation for the larvae treated with MNU at 2Â mM (black line) and 6.7Â mM (gray line). The mode of the spot size (solid arrows; 1.8 for 2Â mM MNU and 2.2 for 6.7Â mM MNU) and the average of the spot size (dotted arrows; 3.6 for 2Â mM MNU and 4.1 for 6.7Â mM MNU) for each dose were calculated from each polynomial approximation curve after the subtraction of the spot number without irradiation. (C) The relationship between the number of AO-stained clusters per wing and the mode of the spot size (solid lines) or the average of the spot size (dotted lines). The concentrations of MNU were 2Â mM (black circles) and 6.7Â mM (gray circles)Back to article page