Table 2 Apoptosis and mutation induced by MNU and ENU for 6 h in wild-type Drosophila (mwh/flr)

Apoptosis (number of clusters stained with AO/disc)

Time post-treatment (h)

  0

28.6 ± 11.0

 74.6 ± 30.5

 95.7 ± 19.1

 54.6 ± 20.7

 60.8 ± 22.7

  6

54.8 ± 18.9

223.1 ± 74.2

274.8 ± 110.6

180.2 ± 58.6

289.5 ± 74.3

  12

78.7 ± 26.7

199.7 ± 66.6

316.1 ± 85.4

201.9 ± 66.1

263.7 ± 86.5

  18

35.2 ± 12.8

118.9 ± 80.9

256.7 ± 91.1

117.4 ± 42.4

162.3 ± 46.7

  24

41.3 ± 19.0

116.8 ± 46.6

196.7 ± 54.2

121.4 ± 39.2

160.2 ± 67.7

Mutation (number of total spots/wing)

0.49

7.96**

28.6**

10.2**

15.1**

Survival (%)

100

100

44.9

83.2

77.1