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Table 6 Apoptosis and mutation induced by monochromatic UV light in NER-deficient Drosophila (mus201; mwn/flr)

From: Mutation and apoptosis are well-coordinated for protecting against DNA damage-inducing toxicity in Drosophila

 

Wavelength (nm)

 

Control

310

320

330

340

360

Fluence (kJ/m2)

0

0.93

10

302

315

330

Apoptosis (number of clusters stained with AO/disc)

Time post-exposure (h)

  0

-

 49.9 ± 15.4

36.5 ±  9.7

 60.2 ± 32.4

57.6 ± 17.2

62.6 ± 25.4

  6

49.1 ± 18.1

 86.3 ± 63.9

59.0 ± 30.8

114.6 ± 46.3

76.4 ± 22.4

44.1 ± 20.7

  12

54.6 ±  7.9

131.2 ± 61.6

80.0 ± 34.5

122.5 ± 54.4

60.2 ± 21.9

37.8 ± 18.0

  18

29.4 ± 6.4

116.8 ± 83.3

60.0 ± 30.7

 86.3 ± 46.2

78.7 ± 32.1

34.8 ± 12.1

  24

25.5 ± 8.6

129.0 ± 46.0

55.4 ± 31.8

 78.6 ± 23.5

60.2 ± 24.9

34.5 ± 17.2

Mutation (number of total spots/wing)

 

0.53

2.30**

1.47**

1.02**

0.76**

0.82*

The number of AO clusters at 6 h/wing/kJ/m2

 

-

92.8

5.90

0.379

0.243

0.134

Total spots/wing/J/m2

 

-

2.473

0.147

0.00338

0.00241

0.00248

  1. *P < 0.05, **P < 0.01, a significant difference from the control