Fig. 1
From: Development of a micronucleus test using the EpiAirway™ organotypic human airway model
Optimization of incubation with cytochalasin B in the EpiAirway™ model. a Schematic of the incubation conditions with cytochalasin B (CB) for 48 or 72 h. b Percentage of binucleated cells (%BNCs) obtained after incubation with at 0, 1, 3, and 5 μg/mL for 48 h (in light blue) or 72 h (in blue). c Schematic of the incubation conditions with CB for 72 or 120 h. d %BNCs obtained after incubation with CB at 0, 3, and 10 μg/mL for 72 h (in blue) or 120 h (in deep blue). Values are means ± standard deviation of triplicate inserts