Table 1 Distribution of mean γH2AX foci/cell ± SD in PBMCs of individuals from NLNRA and different dose groups of HLNRA
Area (Dose in mGy/year) | n | Age (years ± SD) | Mean Dose (mGy/y ± SD) and Range | Total no. of Cells scored (no. of γH2AX foci observed) | Mean γH2AX foci/ cell ± SD | Number of cells with | ||||
|---|---|---|---|---|---|---|---|---|---|---|
1 γH2AX focus (%) | 2 γH2AX foci (%) | 3 γH2AX foci (%) | 4 γH2AX foci (%) | 5 γH2AX foci (%) | ||||||
NLNRA (≤ 1.50) | 50 | 39.2 ± 8.4 | 1.21 ± 0.21 (0.57–1.49) | 13,221 (1181) | 0.090 ± 0.051 | 990 (7.49) | 68 (0.51) | 17 (0.13) | 1 (0.01) | 0 (0) |
HLNRA (> 1.50) | 150 | 37.7 ± 8.2 | 10.52 ± 7.93 1.57–39.88 | 39,002 (3553) | 0.096 ± 0.051 | 2729 (7.00) | 281 (0.72) | 57 (0.15) | 14 (0.04) | 7 (0.02) |
NLNRA + HLNRA | 200 | 38.1 ± 8.3 | 8.19 ± 7.96 (0.57–39.88) | 52,223 (4734) | 0.092 ± 0.047 | 3719 (7.12) | 349 (0.67) | 74 (0.14) | 15 (0.03) | 7 (0.01) |
HLNRA dose groups (mGy/year) | ||||||||||
1.51-5.0 | 50 | 35.9 ± 8.5 | 3.02 ± 0.95 (1.57–4.93) | 13,055 (1225) | 0.096 ± 0.051 | 913 (6.99) | 107 (0.82) | 15 (0.11) | 7 (0.05) | 5 (0.04) |
5.01-10.0 | 30 | 35.7 ± 8.1 | 7.43 ± 1.48 (5.01–9.75) | 8169 (617) | 0.076 ± 0.036 | 504 (6.17) | 44 (0.54) | 7 (0.09) | 1 (0.01) | 0 (0) |
10.01-15.0 | 33 | 38.6 ± 7.5 | 12.22 ± 1.47 (10.21–14.99) | 8637 (746) | 0.087 ± 0.042 | 578 (6.69) | 55 (0.64) | 15 (0.17) | 2 (0.02) | 1 (0.01) |
> 15.0 | 37 | 40.9 ± 7.9 | 21.64 ± 6.28 (15.26–39.88) | 9141 (965) | 0.108 ± 0.046 | 734 (8.03) | 75 (0.82) | 20 (0.22) | 4 (0.04) | 1 (0.01) |