Skip to main content

Table 2 Distribution of mean γH2AX foci/cell ± SD according to age of the donor and personal habits

From: Non-linear dose response of DNA double strand breaks in response to chronic low dose radiation in individuals from high level natural radiation areas of Kerala coast

Characteristics

n

Mean Age in years ± SD

Mean dose in mGy/y ± SD

Total no. of Cells scored (no. of γH2AX foci observed)

Mean γH2AX foci/ cell ± SD

Number of cells with

1 γH2AX focus (%)

2 γH2AX foci (%)

3 γH2AX foci (%)

4 γH2AX foci (%)

5 γH2AX foci (%)

Age years ≤ 29

 31

26.0 ± 3.6

6.37 ± 5.53

8366 (789)

0.098 ± 0.042

578 (6.91)

79 (0.94)

13 (0.16)

1 (0.01)

2 (0.02)

 30–34

39

31.7 ± 1.4

6.87 ± 5.97

10,182 (790)

0.078 ± 0.037

647 (6.35)

47 (0.46)

12 (0.12)

2 (0.02)

1 (0.01)

 35–39

45

36.9 ± 1.5

7.08 ± 6.91

11,838 (977)

0.084 ± 0.042

787 (6.65)

63 (0.53)

11 (0.09)

4 (0.03)

3 (0.03)

 40–44

36

42.0 ± 1.5

9.22 ± 9.08

9241 (892)

0.099 ± 0.058

730 (7.9)

59 (0.64)

12 (0.13)

2 (0.02)

0 (0)

 45–49

29

46.8 ± 1.3

12.65 ± 9.73

7410 (694)

0.097 ± 0.06

541 (7.3)

47 (0.63)

14 (0.19)

3 (0.04)

1 (0.01)

 ≥ 50

20

52.0 ± 2.8

7.76 ± 9.87

5186 (592)

0.114 ± 0.033

436 (8.41)

54 (1.04)

12 (0.23)

3 (0.06)

0 (0)

Smoking - No

122

37.5 ± 8.6

7.8 ± 7.35

32,256 (2911)

0.092 ± 0.047

2288 (7.09)

213 (0.66)

41 (0.13)

11 (0.03)

6 (0.02)

Smoking - Yes

78

38.9 ± 7.7

8.8 ± 8.85

19,967 (1823)

0.093 ± 0.048

1431 (7.17)

136 (0.68)

33 (0.17)

4 (0.02)

1 (0.01)

Drinking No

56

38.2 ± 9.4

7.77 ± 8.6

15,124 (1403)

0.096 ± 0.052

1062 (7.02)

109 (0.72)

25 (0.17)

7 (0.05)

4 (0.03)

Drinking - Yes

144

38.0 ± 7.9

8.35 ± 7.72

37,099 (3331)

0.091 ± 0.045

2657 (7.16)

240 (0.65)

49 (0.13)

8 (0.02)

3 (0.01)

Total

200

38.1 ± 8.3

8.19 ± 7.96

52,223 (4734)

0.092 ± 0.047

3719 (7.12)

349 (0.67)

74 (0.14)

15 (0.03)

7 (0.01)

  1. Comparison of γH2AX frequency across age groups: F5,194 = 2.17; P = 0.059;
  2. Comparison of γH2AX frequency between smokers and non-smokers: t198 = 0.13; P = 0.895;
  3. Comparison of γH2AX frequency between those who do and do not consume alcoholic drinks: t198 = 0.62; P = 0.538