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Fig. 9 | Genes and Environment

Fig. 9

From: An in vitro method for detecting genetic toxicity based on inhibition of RNA synthesis by DNA lesions

Fig. 9

RT-qPCR analysis of transcripts from cisplatin-treated DNA templates. a Scheme for detecting transcription inhibition from cisplatin-treated DNA templates (drug/nucleotide ratio = 0.005). b Melting curve of RT-qPCR products from RNA transcripts of cisplatin-treated DNA templates. Each reaction was run in triplicate. c Amplification plot of RT-qPCR analysis of RNA transcripts of cisplatin-treated DNA templates. Each reaction was run in triplicate. d Relative fold change of transcripts from mock (set as 1.0) and cisplatin-treated DNA templates. Data show the mean of three samples ± standard deviation (SD)

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Genes and Environment

ISSN: 1880-7062

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