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Fig. 3 | Genes and Environment

Fig. 3

From: Weight of evidence approach using a TK gene mutation assay with human TK6 cells for follow-up of positive results in Ames tests: a collaborative study by MMS/JEMS

Fig. 3

Target gene ontology analysis for TK6 cells exposed to 4-nitroanthranilic acid for 24 h. Whereas no significance was found in GO:0006974 (cellular response to DNA damage stimulus), GO:0006281 (DNA repair), and GO:0006979 (response to oxidative stress), statistically significance was found in GO:0008631 ~ intrinsic apoptotic signaling pathway in response to oxidative stress among DEPs in 24 h 800 μg/mL group and specific DEPs in 24 h 800 μg/mL group, indicating involvement with oxidative stress

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Genes and Environment

ISSN: 1880-7062

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