Folate metabolism modifies chromosomal damage induced by 1,3-butadiene: results from a match-up study in China and in vitro experiments

Table 1 PCR primers and restricted endonucleases for MTHFR gene in genotyping process

SNP	Primers		PCR method	Restricted endonucleases
SNP	Forward	Reverse
MTHFR 677	5′-TGAAGGAGAAGGTGTCTGCGGGA-3′	5′-AGGACGGTGCGGTGAGAGTG-3’	RFLP	Hinf1
MTHFR 1298	5′-CTTTGGGAGCTGAAGGACTAC-3’	5′-CACTTTGTGACCATTCCGGTTTG-3’	RFLP	Mbo2

ISSN: 1880-7062