Fig. 8From: Mutation and apoptosis are well-coordinated for protecting against DNA damage-inducing toxicity in DrosophilaApoptosis and mutation induced by monochromatic UV light in NER-deficient Drosophila (mus201; mwh/flr). (A) The profiles of apoptosis induced by UV irradiation with 310-nm light at 0.93Â kJ/m2 (closed circles), 320-nm light at 10Â kJ/m2 (open circles), 330-nm light at 302Â kJ/m2 (closed triangles), 340-nm light at 315Â kJ/m2 (open triangles), 360-nm light at 330Â kJ/m2 (closed diamonds), or no irradiation (cross). (B) The relationship between the number of AO-stained clusters per wing and total spots per wing at each wavelength (symbols are the same as in panel (A)). (C) The action spectra of the mutagenicity determined as the total spots per wing normalized by the UV fluence (kJ/m2), and apoptosis inducibility (open circles), which was determined as the number of clusters per wing disc at 6Â h normalized by the UV fluence (kJ/m2; closed circles)Back to article page