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Table 5 Association of EGFR rs121434568 genotype and alleles with risk of NSCLC susceptibility

From: Detection of EGFR gene polymorphisms in non-small cell lung cancer Egyptian patients: a case–control study

EGFR

exon 21

(T > G)

Control

n = 124

NSCLC patient

n = 124

P

OR

(95% CI)

n

%

n

%

Genotype

TT

109

87.9

81

65.3

Wild type

TG

15

12.1

38

30.6

 < 0.001

2.104

(1.406 -3.147)

GG

0

0

5

4

1

 

TG + GG

15

12.1

43

31

 < 0.001

2.301

(1.555–3.405)

Allele

T

233

94.0

200

80.6

Wild type

G

15

6.0

48

19.4

 < 0.001

2.125

(1.460 -3.091)

  1. P probability
  2. p < 0.05 is significant; Odds ratio [OR]; Confidence interval [CI], Logistic regression analysis was used
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Genes and Environment

ISSN: 1880-7062

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