Fig. 1

The apoptosis assessment of curcuminoid analogues (FLDP-5 and FLDP-8) and curcumin on LN-18 cells. A FLDP-5 curcuminoid analogue was treated on LN-18 cells with concentrations from 0.625 µM to 10 µM and was observed after 24-h treatment. B FLDP-8 curcuminoid analogue was treated on LN-18 cells with concentrations from 0.625 µM to 10 µM and was observed after 24-h treatment. C Curcumin was treated on LN-18 cells with concentrations from 6.25 µM to 100 µM and was observed after 24-h treatment. D Cytograms of curcuminoid analogues (FLDP-5 and FLDP-8) and curcumin at a concentration that induced ± 50% of apoptosis on LN-18 cells after 24-h. The cytograms represent the typical profile of three independent experiments. Each data point was obtained from three independent experimental replicates and expressed as mean ± SEM of the percentage of cells. *p < 0.05 against negative control, NEG (untreated cell)