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Fig. 3 | Genes and Environment

Fig. 3

From: Astaxanthin suppresses the malignant behaviors of nasopharyngeal carcinoma cells by blocking PI3K/AKT and NF-κB pathways via miR-29a-3p

Fig. 3

Astaxanthin upregulates miR-29a-3p expression to inactivate the PI3K/AKT and NF-κB pathways.A. miR-29a-3p expression in head and neck squamous cell carcinoma (HNSC) samples and normal samples was analyzed by the tool ENCORI, encyclopedia of RNA interactomes. B. miR-29a-3p expression in C666-1 cells treated with or without astaxanthin was measured by RT-qPCR. C. After transfection of mimics into C666-1 cells, RT-qPCR was performed to assess miR-29a-3p expression in miR-29a-3p mimics or NC mimics groups. D. Western blotting was conducted to measure protein levels of factors associated with PI3K/AKT or NF-κB signaling pathways in C666-1 cells transfected with miR-29a-3p mimics or NC mimics. ***p<0.001.

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