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Table 2 Details of the 19 base substitutions called at the first screening in the control sample

From: Mutation assay using single-molecule real-time (SMRTTM) sequencing technology

Reference position Reference Forward read Reverse read Comment Judgement p-value**
Most dominant allele Coverage Read count p-value* Most dominant allele Coverage Read count p-value*
999271 C C 33 23 3.9E-20 T 36 30 5.5E-31   Mismatch 0
4778252 T T 17 16 9.1E-19 A 19 19 4.4E-23   Mismatch 0
3355477 0047 C 13 12 4.4E-14 G 11 10 1.0E-11   Mismatch 1.0E-11
536849 C C 9 9 2.5E-11 T 9 9 2.5E-11   Mismatch 5.0E-11
1051080 G A 10 9 1.6E-10 G 10 9 1.6E-10   Mismatch 3.1E-10
3287776 A T 11 8 8.2E-08 A 12 11 6.7E-13   Mismatch 8.2E-08
3823422 C C 7 4 5.7E-03 G 11 10 1.0E-11   Mismatch 5.7E-03
316363 G          edge of map No  
694963 C          edge of map No  
918766 G          edge of map No  
1922859 C          edge of map No  
4423790 C          edge of map No  
4144134 C          No mutation No  
4515279 C          No mutation No  
290717 C          original allele No  
1760048 A          original allele No  
1760052 A          original allele No  
3741045 T          original allele No  
4099877 G          original allele No  
  1. *Probability that the real allele is not the most dominant allele
  2. **Probability that the Judgement is not correct