- Kawai et al. has won Genes & Environment Best Paper Award 2018 for their article "Measurement of 8-hydroxyguanine as an oxidative stress biomarker in saliva by HPLC-ECD."
- [new Article Collection] JEMS Open Symposia 2017&2018: “Challenges of Young Scientists”
- Genes and Environment accepted for inclusion in Clarivate Analytics's Emerging Source Citation Index (ESCI).
[Pick Up] Standard protocol for the total red blood cell Pig-a assay used in the interlaboratory trial organized by the Mammalian Mutagenicity Study Group of the Japanese Environmental Mutagen Society
The Pig-a assay, a promising tool for evaluating in vivo genotoxicity, is based on flow cytometric enumeration of red blood cells (RBCs) that are deficient in glycosylphosphatidylinositol anchor protein. Various approaches for measuring Pig-a mutant cells have been developed, particularly focusing on measuring mutants in peripheral RBCs (called the RBC Pig-a assay) and reticulocytes (the PIGRET assay). To verify the potential and usefulness of these assays for short-term testing, inter-laboratory trial involving 16 laboratories were conducted.
In this article, the authors describe the standard protocol for the RBC Pig-a assay used in the inter-laboratory trial.
JEMS Open Symposia 2017&2018: “Challenges of Young Scientists”
Collection published 14 February 2019
10th Anniversary Special Issue
Collection published 1 July 2016
JEMS Open Symposium 2015: “Life Style and Cancer”
Collection published: 22 January 2016
Asian Conference on Environmental Mutagens (ACEM2014)
Collection published: 1 August 2015
Aims and scope
Genes and Environment is an open access, peer-reviewed journal that aims to accelerate communications among global scientists working in the field of genes and environment. The journal publishes articles across a broad range of topics including environmental mutagenesis and carcinogenesis, environmental genomics and epigenetics, molecular epidemiology, genetic toxicology and regulatory sciences.
About the Editor
Masami Yamada studied bacterial genetics and got a PhD degree from Osaka University. Since 1990, using genetic engineering techniques, she has constructed many strains from standard tester strains for the Ames test at the National Institute of Health Sciences, Tokyo. Such strains are useful for research fields on environmental mutagens.
Strain requests come to her every year from domestic, Asia, Europe, North America, South America, and other countries. Currently, she teaches Biology and Genetic Engineering at National Defense Academy of Japan.
Acknowledgement and information
-Publication of Genes and Environment is partly supported by the Japan Society of Promotion of Science Grant-in-Aid for Publication of Scientific Research Results, aka KAKENHI. (Grant Number 17HP2002).
-Genes and Environment archive of papers published before 2015 are available at: https://www.jstage.jst.go.jp/browse/jemsge
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