Genes and Environment

Polymorphism in autophagy-related genes LRP1 and CAPZA1 may promote gastric mucosal atrophy

Naoyuki Yamaguchi, Takuki Sakaguchi, Hajime Isomoto, Tatsuo Inamine, Ryoya Tsukamoto, Daisuke Fukuda, Ken Ohnita, Tsutomu Kanda, Kayoko Matsushima, Tatsuro Hirayama, Kazuo Yashima & Kazuhiro Tsukamoto 

Helicobacter pylori secretes cytotoxin-associated gene A (CagA) into the gastric epithelium, causing gastric mucosal atrophy (GMA) and gastric cancer. In contrast, host cells degrade CagA via autophagy. However, the association between polymorphisms in autophagy-related genes and GMA must be fully elucidated.

Read this article: Volume 45, Article number: 18 (2023)

Non-linear dose response of DNA double strand breaks in response to chronic low dose radiation in individuals from high level natural radiation areas of Kerala coast

Vinay Jain, Divyalakshmi Saini, D. C. Soren, V. Anil Kumar, P. R. Vivek Kumar, P. K. M. Koya, G. Jaikrishan & Birajalaxmi Das

The human population living in high level natural radiation areas (HLNRAs) of Kerala coast provide unique opportunities to study the biological effects of low dose and low dose rate ionizing radiation below 100 mGy. The present study evaluated dose response relationship between DNA double strand breaks (DSBs) and background radiation dose in individuals residing in Kerala coast. 

Read this article Volume 45, Article number: 16 (2023)

• Lessons Learned from Japanese Association for Cancer Prevention and Future Opportunities
• Current topics in China for Environmental Mutagen Research
• G&E Best Paper Award collection
• Special Issue in memory of Takashi Sugimura 
• Asian Conference on Environmental Mutagens (ACEM2019)
• Article collection: Meeting Reports: collection of various meeting reports published in G&E
• Article collection: Genotoxicity Tests
• JEMS Open Symposia 2017&2018: “Challenges of Young Scientists”
• 10th Anniversary Special Issue
• JEMS Open Symposium 2015: “Life Style and Cancer”
• Asian Conference on Environmental Mutagens (ACEM2014)

Masami Yamada studied bacterial genetics and got a PhD degree from Osaka University. Since 1990, using genetic engineering techniques, she has constructed many strains from standard tester strains for the Ames test at the National Institute of Health Sciences, Tokyo. Such strains are useful for research fields on environmental mutagens.
Strain requests come to her every year from domestic, Asia, Europe, North America, South America, and other countries. Currently, she teaches Biology and Genetic Engineering at National Defense Academy of Japan.

APC Discount for JEMS members
Members of Japanese Environmental Mutagen and Genome Society(JEMS)  are entitled to receive discount on Article Processing Charge. 

Free APC for researchers in Asia
We now offer a full APC waiver to the submissions from the countries where Asian Association of the Environmental Mutagen Societies (AAEMS)–partnering societies are located (excluding Japan). Those countries are Australia, China, India, Iran, South Korea, Philippines and Thailand.

To request APC discount (new process as from March 2023)
Authors are no longer requested to submit membership code during submission.
Please take following step to receive APC discount.
1) After manuscript submission, corresponding author informs EIC (editor@j-ems.org) of the manuscript number and membership number. 
2) When the manuscript was accepted for publication, author receives URL and asked to complete post-acceptance process. 
3) During post-acceptance process author requests APC discount by requsting 'Shared Support' on journal partner page.
4) EIC approves the request and discount is granted. 
5) Author pays discounted APC. 

see also
-information for JEMS members (in Japanese) 
-Post acceptance workflow process (Author Journey)

*those authors who were offered full APC coverage by the editor (for invited/solicited papers), please select 'Prepay for invited papers' to receive full coverage.