Genes and Environment

Genoprotective potential of Macaranga species phytochemical compounds on HT-29 human colorectal adenocarcinoma cell line

Ee Ling Siew, Lishantini Pearanpan, Zhafri Zamkhuri, Fariza Juliana Nordin, Theng Choon Ooi, Kok Meng Chan, Aisyah Salihah Kamarozaman, Norizan Ahmat & Nor Fadilah Rajab

The species of genus Macaranga are widely found in Malaysian secondary forests and has been used as an alternative for treating varieties of illness. Studies have shown that the medicinal properties of this genus contain anti-inflammatory, antioxidant, and anti-cancer effects. This study aimed to determine the cytotoxicity of six isolated phytochemicals from Macaranga heynei (M. heynei), Macaranga lowii and Shorea leprosula on HT-29 human colorectal adenocarcinoma cell lines.

Read this article: Volume 45, Article number: 28 (2023)

Detection of in vivo mutagenicity in rat liver samples using error-corrected sequencing techniques

Kazuki Izawa, Masataka Tsuda, Takayoshi Suzuki, Masamitsu Honma & Kei-ichi Sugiyama 

Authors investigated the use of a next-generation sequencing technique called paired-end and complementary consensus sequencing (PECC-Seq) for detecting in vivo mutagenicity in rat liver samples. This approach offers a labor- and time-efficient alternative to conventional methods, potentially advancing regulatory science for substance safety assessment.

Read this article Volume 45, Article number: 30 (2023) 

• Lessons Learned from Japanese Association for Cancer Prevention and Future Opportunities
• Current topics in China for Environmental Mutagen Research
• G&E Best Paper Award collection
• Special Issue in memory of Takashi Sugimura 
• Asian Conference on Environmental Mutagens (ACEM2019)
• Article collection: Meeting Reports: collection of various meeting reports published in G&E
• Article collection: Genotoxicity Tests
• JEMS Open Symposia 2017&2018: “Challenges of Young Scientists”
• 10th Anniversary Special Issue
• JEMS Open Symposium 2015: “Life Style and Cancer”
• Asian Conference on Environmental Mutagens (ACEM2014)

Masami Yamada studied bacterial genetics and got a PhD degree from Osaka University. Since 1990, using genetic engineering techniques, she has constructed many strains from standard tester strains for the Ames test at the National Institute of Health Sciences, Tokyo. Such strains are useful for research fields on environmental mutagens.
Strain requests come to her every year from domestic, Asia, Europe, North America, South America, and other countries. Currently, she teaches Biology and Genetic Engineering at National Defense Academy of Japan.

APC Discount for JEMS members
Members of Japanese Environmental Mutagen and Genome Society(JEMS)  are entitled to receive discount on Article Processing Charge. 

Free APC for researchers in Asia
We now offer a full APC waiver to the submissions from the countries where Asian Association of the Environmental Mutagen Societies (AAEMS)–partnering societies are located (excluding Japan). Those countries are Australia, China, India, Iran, South Korea, Philippines and Thailand.

To request APC discount (new process as from March 2023)
Authors are no longer requested to submit membership code during submission.
Please take following step to receive APC discount.
1) After manuscript submission, corresponding author informs EIC (editor@j-ems.org) of the manuscript number and membership number. 
2) When the manuscript was accepted for publication, author receives URL and asked to complete post-acceptance process. 
3) During post-acceptance process author requests APC discount by requsting 'Shared Support' on journal partner page.
4) EIC approves the request and discount is granted. 
5) Author pays discounted APC. 

*those authors who were offered full APC coverage by the editor (for invited/solicited papers), should select 'Prepay for invited papers' to receive full coverage. 

see also
-Changes in Submission Process (in Japanese)
-Post acceptance workflow process (Author Journey)