- Best Paper Award 2022 has been awareded to Kawada et al. "Analysis of nucleotide insertion opposite urea and translesion synthesis across urea by DNA polymerases."
- [For JEMS members] New process to request APC discount. Members are no longer requested to submit institution code to request APC discount during manuscript submission. Please see below 'Information for Authors' section for further information.
- Updated Aims & Scope: to enhance the quality of Genes and Environment and its contents, the Journal has updated and revised its Aims and Scope.
Formation of the mutagenic DNA lesion 1,N2-ethenoguanine induced by heated cooking oil and identification of causative agents
Hiroshi Kasai & Kazuaki Kawai
Epidemiological studies have consistently shown that diet plays a significant role in developing human cancer. Notably, the consumption of fried food has been associated with an increased risk of various cancers. Information about the carcinogens and DNA-damaging agents in fried foods remains limited, except for acrolein and acrylamide, both being classified as Group 2A (i.e., probable human carcinogens) by the International Agency for Research on Cancer.
This study sought to identify the cancer-causing agents by extensively investigating guanine modifications induced by heated cooking oil as a model for DNA damage.
[Featured Article]: Best Paper Award 2022
Analysis of nucleotide insertion opposite urea and translesion synthesis across urea by DNA polymerases
Taishu Kawada, Katsuhito Kino, Kyousuke Tokorodani, Ryuto Anabuki, Masayuki Morikawa, Takanobu Kobayashi, Kazuaki Ohara, Takayuki Ohshima & Hiroshi Miyazawa
In this article, authors describe their studies of nucleotide incorporations and translesion synthesis in relation to Ua with DNA polymerases α, δ, ε, η, ζ and Dpo4. Also, authors confirmed nucleotide incorporation and extension in relation to Ua using Kf exo− and DNA polymerase β.
Read this article: Volume 44, Article number: 7 (2022)
Article collections and Special Issues
- Lessons Learned from Japanese Association for Cancer Prevention and Future Opportunities
- Current topics in China for Environmental Mutagen Research
- G&E Best Paper Award collection
- Special Issue in memory of Takashi Sugimura
- Asian Conference on Environmental Mutagens (ACEM2019)
- Article collection: Meeting Reports: collection of various meeting reports published in G&E
- Article collection: Genotoxicity Tests
- JEMS Open Symposia 2017&2018: “Challenges of Young Scientists”
- 10th Anniversary Special Issue
- JEMS Open Symposium 2015: “Life Style and Cancer”
- Asian Conference on Environmental Mutagens (ACEM2014)
About the Editor
Masami Yamada studied bacterial genetics and got a PhD degree from Osaka University. Since 1990, using genetic engineering techniques, she has constructed many strains from standard tester strains for the Ames test at the National Institute of Health Sciences, Tokyo. Such strains are useful for research fields on environmental mutagens.
Strain requests come to her every year from domestic, Asia, Europe, North America, South America, and other countries. Currently, she teaches Biology and Genetic Engineering at National Defense Academy of Japan.
Low-dose radiation from A-bombs elongated lifespan and reduced cancer mortality relative to un-irradiated individuals
Aims and scope
Genes and Environment is an open-access, peer-reviewed journal that aims to accelerate communications among global scientists working in the fields of genes and environment. The journal welcomes papers dealing with those topics that are relevant to the environment, such as mutagenesis and carcinogenesis, genomics and epigenetics, molecular epidemiology and genetic toxicology, and regulatory sciences.
The mission of the Japanese Environmental Mutagen and Genome Society (JEMS) is to discover how environmental mutagens affect all organisms, and to promote and apply this knowledge to protect human health and our environment. JEMS was founded in 1972, and since then the society has hosted annual conferences and open symposia on timely topics. The society is a member of the Asian Association of the Environmental Mutagen Societies and the International Association of Environmental Mutagenesis and Genomics Societies.
Acknowledgement and information
-Publication of Genes and Environment is partly supported by the Japan Society of Promotion of Science Grant-in-Aid for Publication of Scientific Research Results, aka KAKENHI. (Grant Number 17HP2002).
-Genes and Environment archive of papers published before 2015 are available at: https://www.jstage.jst.go.jp/browse/jemsge
Genes and Environment is an official journal of The Japanese Environmental Mutagen and Genome Society (JEMS).
2022 Citation Impact
1.7 - 2-year Impact Factor
1.9 - 5-year Impact Factor
0.563 - SNIP (Source Normalized Impact per Paper)
0.537 - SJR (SCImago Journal Rank)
11 days submission to first editorial decision for all manuscripts (Median)
94 days submission to accept (Median)
578 Altmetric mentions