Fig. 1From: Genetic influences on nicotinic α5 receptor (CHRNA5) CpG methylation and mRNA expression in brain and adipose tissue CHRNA5 mRNA expression in the putamen compared across rs7164030 genotypes, as measured by qPCR. Samples homozygous for the major “A” allele (A/A) of rs7164030 have approximately 3.5-fold less CHRNA5 mRNA versus samples homozygous for the minor “G” allele, with heterozygotes exhibiting intermediate levels (ANOVA p=1.82×10−6)Back to article page