Table 2 Linear regression results for CpG methylation and CHRNA5 gene expression across rs7164030 genotypes
Dataset | CpG probe | rs7164030 genotype (n) | Standardized β coefficient for methylation | t-value | p-value |
|---|---|---|---|---|---|
BrainCloud | cg22563815 | A/A (118) | 0.267 | 0.363 | 0.717 |
cg22563815 | A/G (77) | 1.166 | 0.390 | 0.698 | |
cg22563815 | G/G (25) | −16.837 | −0.397 | 0.700 | |
cg17108064 | A/A (118) | −0.171 | −1.424 | 0.157 | |
cg17108064 | A/G (77) | 0.153 | 1.072 | 0.288 | |
cg17108064 | G/G (25) | 0.024 | −0.040 | 0.969 | |
MuTHER | cg22563815 | A/A (184) | 4.069 | 0.528 | 0.598 |
cg22563815 | A/G (270) | 0.010 | 0.014 | 0.989 | |
cg22563815 | G/G (111) | −2.964 | −1.718 | 0.089 | |
cg17108064 | A/A (184) | 0.981 | 0.398 | 0.691 | |
cg17108064 | A/G (270) | −1.288 | −0.813 | 0.417 | |
cg17108064 | G/G (111) | −2.510 | −0.639 | 0.524 |