Table 5 Distribution of CYP1A1 polymorphisms in heavy (pack year ≥ 20) vs. light (pack year < 20) smoking in lung cancer patients and control
CYP1A1 variant | Smoking heaviness | Likelihood ratio | |||||
|---|---|---|---|---|---|---|---|
Control | patients | ||||||
Light | heavy | Light | heavy | ratio | P-value | ||
N = 16 | N = 14 | N = 37 | N = 56 | ||||
CYP1A1*2C | N (%) | 0 (0) | 1 (7) | 1 (2.7) | 9 (16.1) | 15.86 | 0.07 |
CYP1A1*4 | N (%) | 1 (6.3) | 3 (21.4) | 12 (32.4) | 19 (33.9) | ||
CYP1A1*2C/*4 | N (%) | 0 (0) | 0 (0) | 0 (0) | 1 (1.8) | ||
wild type | N (%) | 15 (93.8) | 10 (71.4) | 24 (64.9) | 27 (48.2) | ||