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Table 5 Distribution of CYP1A1 polymorphisms in heavy (pack year ≥ 20) vs. light (pack year < 20) smoking in lung cancer patients and control

From: Genetic polymorphisms of human cytochrome P450 CYP1A1 in an Egyptian population and tobacco-induced lung cancer

CYP1A1 variant Smoking heaviness Likelihood ratio
Control patients
Light heavy Light heavy ratio P-value
N = 16 N = 14 N = 37 N = 56
CYP1A1*2C N (%) 0 (0) 1 (7) 1 (2.7) 9 (16.1) 15.86 0.07
CYP1A1*4 N (%) 1 (6.3) 3 (21.4) 12 (32.4) 19 (33.9)
CYP1A1*2C/*4 N (%) 0 (0) 0 (0) 0 (0) 1 (1.8)
wild type N (%) 15 (93.8) 10 (71.4) 24 (64.9) 27 (48.2)