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Table 7 Effects of CYP1A1 polymorphisms on disease prognosis of available follow up cases

From: Genetic polymorphisms of human cytochrome P450 CYP1A1 in an Egyptian population and tobacco-induced lung cancer

CYP1A1 variant Response (n = 22) Chi P
Complete response Partial response Progression Refractory disease Regression Stable disease
N (%) N (%) N (%) N (%) N (%) N (%)
CYP1A1*2C 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0)
CYP1A1*4 0 (0) 0 (0) 2 (22.2) 0 (0) 1 (25.0) 1 (25.0) 6.8 0.33
CYP1A1*2C/*4 0 (0) 0 (0) 1 (11.1) 0 (0) 0 (0) 0 (0) 3.08 0.79
wild type 2 (100) 2 (100) 6 (66.7) 1 9(100) 3 (75.0) 3 (75.0) 12.2 0.052