Table 7 Effects of CYP1A1 polymorphisms on disease prognosis of available follow up cases
CYP1A1 variant | Response (n = 22) | Chi | P | |||||
|---|---|---|---|---|---|---|---|---|
Complete response | Partial response | Progression | Refractory disease | Regression | Stable disease | |||
N (%) | N (%) | N (%) | N (%) | N (%) | N (%) | |||
CYP1A1*2C | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | – | – |
CYP1A1*4 | 0 (0) | 0 (0) | 2 (22.2) | 0 (0) | 1 (25.0) | 1 (25.0) | 6.8 | 0.33 |
CYP1A1*2C/*4 | 0 (0) | 0 (0) | 1 (11.1) | 0 (0) | 0 (0) | 0 (0) | 3.08 | 0.79 |
wild type | 2 (100) | 2 (100) | 6 (66.7) | 1 9(100) | 3 (75.0) | 3 (75.0) | 12.2 | 0.052 |