Skip to main content

Table 2 List of items that have been added to the designated food additives (As of October 6, 2016)

From: Summarized data of genotoxicity tests for designated food additives in Japan

No.a Name
2 chlorous acid water
4 nitrous oxide
8 calcium l-ascorbate
9 l-ascorbic acid 2-glucoside
13 asparaginase
16 acesulfame potassium
17 acetylated distarch adipate
18 acetylated oxidized starch
19 acetylated distarch phosphate
20 acetaldehyde
24 sodium selenite pentahydrate
25 azoxystrobin
26 advantame
28 β-apo-8′-carotenal
29 (3-amino-3-carboxypropyl) dimethylsulfonium chloride
30 amylalcohol
35 ammonium alginate
36 potassium alginate
37 calcium alginate
44 ammonium isovalerate
46 ion exchange resin
47 isoamylalcohol
51 isoquinoline
54 isovaleraldehyde
55 isobutanol
56 isobutyraldehyde (isobutanal)
57 isopropanol
58 isopentylamine
67 mixture of 2-ethyl-3,5-dimethylpyrazine and 2-ethyl-3,6-dimethylpyrazine
69 2-ethylpyrazine
70 3-ethylpyridine
71 2-ethyl-3-methylpyrazine
72 2-ethyl-5-methylpyrazine
73 2-ethyl-6-methylpyrazine
74 5-ethyl-2-methylpyridine
77 ethers
89 octanoic acid
91 starch sodium octenyl succinate
94 peracetic acid
102 canthaxanthin
106 xylitol (alias xylit)
110 triethyl citrate
113 sodium ferrous citrate (sodium iron citrate)
127 sodium gluconate
128 glutamyl-valyl-glycine
130 monoammonium l-glutamate
132 monocalcium dl- l -glutamate
134 monomagnesium dl-l-glutamate
135 calcium silicate
136 magnesium silicate
140 ketones
150 calcium acetate
156 starch acetate
165 calcium saccharin
168 calcium oxide
169 oxidized starch
172 hypochlorous acid water
174 hypobromous acid water
176 2,3-diethylpyrazine
177 2,3-diethyl-5-methylpyrazine
189 fatty acids
191 aliphatic higher aldehydes (except those generally recognized as highly toxic)
192 aliphatic higher hydrocarbons (except those generally recognized as highly toxic)
193 2,3-dimethylpyrazine
194 2,5-dimethylpyrazine
195 2,6-dimethylpyrazine
196 2,6-dimethylpyridine
201 potassium dl-bitartrate (potassium hydrogen dl-tartrate or potassium hydrogen dl-tartrate)
203 disodium dl-tartrate (disodium dl-tartrate)
226 magnesium hydroxide
227 sucralose (trichlorogalactosucrose)
228 calcium stearate
229 magnesium stearate
231 sodium stearoyl lactylate
236 calcium sorbate
248 thiamine thiocyanate (vitamin B1 thiocyanate)
251 thioethers (except those generally recognized as highly toxic)
252 thiols (thioalcohols) (except those generally recognized as highly toxic)
258 5,6,7,8-tetrahydroquinoxaline
259 2,3,5,6-tetramethylpyrazine
262 terpene hydrocarbons
268 all-racemic -α-tocopheryl acetate
269 R,R,R -α-tocopheryl acetate
272 trimethylamine
273 2,3,5-trimethylpyrazine
276 nisin
277 natamycin
284 carbon dioxide (carbonic acid, gas)
287 potassium lactate
291 neotame
303 valeraldehyde
306 biotin
308 bisbentiamine (benzoylthiamine disulfide)
311 1-hydroxyethylidene-1, 1-diphosphonic acid
313 hydroxycitronellal dimethylacetal
314 hydroxypropyl distarch phosphate
315 hydroxypropyl cellulose
316 hydroxypropyl starch
317 hydroxypropyl methylcellulose
318 piperidine
321 sunflower lecithin
323 pyrazine
325 pyrimethanil
328 pyrrolidine
334 pyrrole
339 2-(3-phenylpropyl) pyridine
340 phenethylamine
341 phenol ethers (except those generally recognized as highly toxic)
342 phenols (except those generally recognized as highly toxic)
343 ferrocyanides (potassium ferrocyanide (potassium hexacyanoferrate (ii)), calcium ferrocyanide (calcium hexacyanoferrate (ii)), sodium ferrocyanide (sodium hexacyanoferrate (ii))
344 butanol
345 butylamine
346 butyraldehyde
350 fludioxonil
352 propanol
353 propionaldehyde
369 2-pentanol (syn: sec-amylalcohol)
370 trans-2-pentenal
371 1-penten-3-ol
372 aromatic alcohols
373 aromatic aldehydes (except those generally recognized as highly toxic)
377 polysorbate 20
378 polysorbate 60
379 polysorbate 65
380 polysorbate 80
381 polyvinylpyrroridone
382 polyvinylpolypyrrolidone
394 5-methylquinoxaline
395 6-methylquinoline
396 6,7-dihydro-5-methyl-5 h-cyclopentapyrazine
398 1-methylnaphthalene
400 2-methypyrazine
401 2-methylbutanol
402 3-methyl-2-butanol
403 2-methylbutyraldehyde
404 trans-2-methyl-2-butenal, (e)-2-methyl-2-butenal
405 3-methyl-2-butenal
406 3-methyl-2-butenol
417 Lactones (except those generally recognized as highly toxic)
422 calcium 5′-ribonucleotide
431 potassium sulfate
439 distarch phosphate
440 monostarch phosphate
443 trimagnesium phosphate (syn: Magnesium phosphate, tribasic)
452 magnesium monohydrogen phosphate
454 phosphated distarch phosphate
  1. anumbers are consistent with those underlined in Table 3