Skip to main content
Fig. 10 | Genes and Environment

Fig. 10

From: High-content imaging analyses of γH2AX-foci and micronuclei in TK6 cells elucidated genotoxicity of chemicals and their clastogenic/aneugenic mode of action

Fig. 10

Scatter plots of the chemicals used in the study. The horizontal axis represents fold increase of MN % from each concurrent control level. The vertical axis shows fold increase of γH2AX focus count per cell from each control level. The broken red lines indicate the thresholds for judging positive or negative for MN or γH2AX foci induction, which were 2-fold of control levels. The non-genotoxins are plotted in the lower-left area, which means neither MN nor γH2AX foci was induced. The clastogens are plotted in the upper-right area, while the aneugens are plotted in the lower-right area. This reflects that clastogens induced both MN and γH2AX, but aneugens induced MN without any induction of γH2AX

Back to article page

Genes and Environment

ISSN: 1880-7062

Contact us