Table 1 The FA gene products and their functions
From: Importance of finding the bona fide target of the Fanconi anemia pathway
| FA protein (alias) | Function |
|---|---|
| FANCA | FA core complex |
| FANCB | FA core complex |
| FANCC | FA core complex |
| FANCD1 (BRCA2) | Homologous recombination |
| FANCD2 | ID complex |
| FANCE | FA core complex |
| FANCF | FA core complex |
| FANCG | FA core complex |
| FANCI | ID complex |
| FANCJ (BRIP1) | Homologous recombination |
| FANCL | FA core complex, ubiquitin ligase |
| FANCM | FA core complex, helicase |
| FANCN (PALB2) | Homologous recombination |
| FANCO (RAD51C) | Homologous recombination |
| FANCP (SLX4) | ICL unhooking |
| FANCQ (ERCC4/XPF) | ICL unhooking, structure-specific endonuclease |
| FANCR (RAD51) | Homologous recombination |
| FANCS (BRCA1) | Homologous recombination |
| FANCT (UBE2T) | Ubiquitin-conjugating enzyme |
| FANCU (XRCC2) | Homologous recombination |
| FANCV (MAD2L2/REV7) | Translesion synthesis |
| FANCW (RFWD3) | Homologous recombination, ubiquitin ligase |