Bisphenol A enhances adipogenic signaling pathways in human mesenchymal stem cells

Genes and Environment

Table 2 Comparison of protein expression in BPA groups vs. control

Proteins	Time	Group	Mean^a	Standard Deviation	Result
FABP4	Day 6	Control	0.27	0.03	X = 6.5 df = 2 P-value = 0.03*
		10⁻⁸ M BPA	0.23	0.05
		10⁻¹⁰ M BPA	0.18	0.02
	Day 14	Control	0.32	0.02	X = 9.04 df = 2 P-value = 0.01*
		10⁻⁸ M BPA	0.18	0.006
		10⁻¹⁰ M BPA	0.2	0.01
GLUT4	Day 6	Control	0.17	0.03	X = 6.5 df = 2 P-value = 0.03*
		10⁻⁸ M BPA	0.14	0.03
		10⁻¹⁰ M BPA	0.11	0.01
	Day 14	Control	0.20	0.01	X = 9.04 df = 2 P-value = 0.01*
		10⁻⁸ M BPA	0.11	0.003
		10⁻¹⁰ M BPA	0.12	0.009
ERβ	Day 6	Control	1.1	0.73	X = 3.84 df = 2 P-value = 0.1^†
		10⁻⁸ M BPA	0.92	0.22
		10⁻¹⁰ M BPA	0.73	0.09
	Day 14	Control	1.29	0.09	X = 9.4 df = 2 P-value = 0.009*
		10⁻⁸ M BPA	0.74	0.02
		10⁻¹⁰ M BPA	0.80	0.06

FABP4 Fatty acid binding proteins-4, GLUT4 Glucose transporter-4, ERβ Estrogen receptor beta
^ang/mg total protein
*Mean values were significantly different between the groups (P < 0.05)
^† Mean values were not significantly different between the groups (P > 0.05)

ISSN: 1880-7062