Skip to main content

Table 2 Level of DNA damage on V79–4 treated cell line with metabolic activation. The results are the means ±SE of at least three separate experiments (*p < 0.05 versus negative control)

From: In vitro toxicological assessment of gadolinium (III) chloride in V79–4 fibroblasts

Level of DNA damage (Arbituary unit)
 TmTD
3 h
Negative control0.42 ± 0.123.46 ± 0.72
Negative control + S90.47 ± 0.093.80 ± 0.66
0.25 mM GdCl30.61 ± 0.064.70 ± 0.30
0.5 mM GdCl30.98 ± 0.076.93 ± 0.34
1.0 mM GdCl30.54 ± 0.083.81 ± 0.63
 TmTD
30 min
Positive control*6.87 ± 0.88*26.40 ± 2.14
 TmTD
24 h
Negative control0.42 ± 0.123.44 ± 0.45
Negative control + S90.66 ± 0.025.31 ± 0.50
0.25 mM GdCl31.15 ± 0.27.25 ± 1.25
0.5 mM GdCl30.97 ± 0.246.83 ± 1.46
1.0 mM GdCl31.32 ± 0.047.48 ± 0.47
 TmTD
30 min
Positive control*6.87 ± 0.88*26.40 ± 2.14