Fig. 2
From: The in vivo role of Rev1 in mutagenesis and carcinogenesis
Model of accelerated chemically-induced tumorigenesis mediated by Rev1 overexpression. Overexpressed Rev1 suppresses apoptosis and increases the mutation frequency after the treatment of chemical reagents. The surviving fraction of mutated cells was higher under Rev1 overexpression, resulting in acceleration of carcinogenesis