Table 2 Odds ration of studies that entered the meta-analysis stage (IL-6 -174 G>C and coronary and IL-6572 C>G and coronary artery disease)

IL-6 -174 G>C and coronary artery disease

Name

GG case group

GG control group

OR

CG case group

CG control group

OR

CC case group

CC control group

OR

Amorim, Fernanda Gobbi

29

41

0.493 (0.254–0.961)

37

27

1.723 (0.885–3.352)

6

3

2.061 (0.495–8.582)

Ansari, Wafa Munir

242

236

0.774 (0.545–1.100)

85

71

1.122 (0.782–1.610)

13

3

4.068 (1.148–14.414)

Babu, Baddela M. V. Srikanth

134

135

0.570 (0.432–0.753)

294

206

0.903 (0.708–1.153)

123

91

0.873 (0.645–1.182)

Banerjee, Indranil

159

171

1.112 (0.723–1.710)

43

57

0.791 (0.505–1.239)

8

4

2.257 (0.670–7.609)

Basso, F.

161

375

0.934 (0.75–1.170)

259

549

1.103 (0.893–1.363)

78

185

0.927 (0.694–1.237)

Bhanushali, A. A.

77

121

0.802 (0.433–1.488)

20

25

1.250 (0.652–2.398)

3

4

1.129 (0.247–5.155)

Chen, H.

155

190

1.168 (0.874–1.560)

218

133

4.665 (3.420–6.364)

56

27

3.135 (1.931–5.089)

Elsaid, A.

23

55

0.433 (0.290–0.647)

55

49

1.991 (1.194–3.320)

26

0

92.188 (5.545–1532.625)

Fan, W. H.

84

129

1.958 (0.048–48.619)

0

1

0.511 (0.021–12.668)

–

–

–

Galimudi, R. K.

72

113

0.433 (0.245–0.766)

102

69

1.976 (1.322–2.955)

26

18

1.511 (0.800–2.854)

Gao, Y. L.

183

224

0.551 (0.378–0.802)

50

47

1.130 (0.729–1.751)

42

15

3.257 (1.761–6.024)

Ghazouani, Lakhdar

298

297

0.911 (0.672–1.237)

110

102

1.064 (0.779–1.455)

10

7

1.397 (0.527–3.706)

Humphries, S. E.

40

827

0.699 (0.484–1.008)

95

1263

1.489 (1.079–2.054)

25

470

0823 (0.531–1.275)

Indumathi, B.

163

145

0.661 (0.448–0.976)

99

57

1.549 (1.044–2.296)

3

3

0.771 (0.154–3.860)

Jabir, N. R

62

63

0.914 (0.483–1.731)

25

23

1.104 (0.569–2.139)

3

3

0989 (0.194–5.034)

Jun, M.

450

503

0.783 (0.648–0.948)

338

311

1.147 (0.944–1.34)

72

48

1.549 (1.062–2.262)

Li, L.

213

245

0.686 (0.508–0.928)

113

105

1.110 (0.809–1.525)

39

15

2.791 (1.510–5.160)

Maitra, A.

36

30

1.2 (0.441–3.267)

10

7

1.310 (0.447–3.838)

0

3

0.115 (0.006–2.301)

Mao, L.

142

193

0.601 (0.408–0.887)

45

45

1.201 (0.760–1.899)

37

22

2.140 (1.221–3.752)

Mastana, S.

105

91

1.366 (0.816–2.287)

32

39

0.717 (0.417–1.232)

1

1

0.951 (0.059–15.352)

Mitrokhin, V.

62

32

1.197 (0.722–1.985)

100

58

1.020 (0.645–1.614)

36

26

0.769 (0.437–1.355)

Nauck, M.

838

230

1.047 (0.877–1.249)

1238

355

0.976 (0.828–1.150)

499

144

0.976 (0.794–1.201)

Omer, W.

13

3

4.068 (1.148–14.414)

85

71

1.122 (0.782–1.610)

242

236

0.774 (0.545–1.1)

Phulukdaree, Alisa

29

34

1.919 (0.827–4.451)

11

19

0.811 (0.337–1.950)

1

8

0.166 (0.020–1.378)

Rios, D. L. S.

254

151

1.072 (0.779–1.476)

126

86

0.850 (0.608–1.168)

34

13

1.652 (0.854–3.194)

43

60

0.759 (0.481–1.2)

92

105

1 (0.668–1.497)

42

37

1.387 (0.844–2.281)

Satti, H. S.

18

38

0.368 (0.150–0.902)

11

14

1.194 (0.468–3.049)

7

0

26.695 (1.472–484.196)

Sekuri, C.

61

57

0.951 (0.560–1.617)

49

41

1.159 (0.676–1.966)

5

7

0636 (0.185–2.824)

Shabana, N. A.

194

96

1.184 (0.850–1.647)

133

90

0.703 (0.501–0.988)

99

33

1.830 (1.185–2.824)

Sun, G. Q.

191

236

0.701 (0.500–0.985)

61

63

1.088 (0.734–1.612)

44

28

1.865 (1.128–3.082)

Tong, Z. C.

201

220

0.884 (0.646–1.212)

87

98

0.903 (0.643–1.267)

38

23

1.824 (1.061–3.136)

Tütün, Ufuk

11

35

0.471 (0.165–1.345)

6

15

0.933 (0.303–2.870)

4

0

25.971 (1.330–507.193)

Wang, K

153

182

0.743 (0.561–0.984)

171

169

1.021 (0.771–1.350)

51

78

1.657 (1.129–2.432)

Yang, H. T.

198

239

0.668 (0.507–0.880)

163

146

1.193 (0.899–1.583)

49

25

2.090 (1.264–3.456)

Yao, H. M.

256

282

0.669 (0.329–1.362)

19

14

1.495 (0.734–3.043)

–

–

–

IL-6572 C>G and coronary artery disease

name

CC case group

CC control group

OR

CG case group

CG control group

OR

GG case group

GG control group

OR

Basso, F.

1

2

1.113 (0.101–12.299)

56

116

1.083 (0.773–1.519)

425

959

0.905 (0.668–1.224)

Chen, H.

228

176

3.487 (2.563–4.743)

158

131

2.192 (1.624–2.958)

43

33

1.849 (1.146–2.985)

Fan, W. H.

42

95

0.368 (0.207–0.656)

38

32

2.530 (1.407–4.547)

4

3

2.117 (0.462–9.706)

Fragoso, J. M.

23

36

0.516 (0.297–0.899)

146

103

1.479 (1.049–2.086)

115

108

0.876 (0.620–1.37)

Gao, Y. L.

114

129

0.862 (0.617–1.204)

134

135

1.063 (0.763–1.481)

27

22

1.306 (0.725–2.354)

Humphries, S. E.

0

9

0.836 (0.048–14.423)

19

225

1.396 (0.849–2.296)

135

2224

0.821 (0.535–1.259)

Jabir, N. R

3

0

7.160 (0.364–140.655)

22

21

1.048 (0.528–2.080)

59

54

1.234 (0.671–2.266)

Jia, X. W.

79

88

0.721 (0.490–1.060)

130

107

1.239 (0.851–1.803)

22

15

1.368 (0.690–2.714)

Jun, M.

427

555

0.545 (0.450–0.662)

337

264

1.460 (1.196–1.781)

96

43

2.393 (1.648–3.475)

Li, L.

132

166

0.679 (0.505–0.914)

165

155

1.118 (0.834–1.498)

68

43

1.715 (1.134–2.592)

Maitra, A.

8

6

1.193 (0.376–3.787)

15

23

0.358 (0.148–0.862)

23

11

2.636 (1..068–6.505)

Mao, L.

81

106

0.823 (0.570–1.189)

110

127

1.010 (0.707–1.445)

33

27

1.491 (0.866–2.567)

Mitrokhin, V.

0

2

0.115 (0.005–2.424)

16

10

0.932 (0.408–2.128)

182

104

1.313 (0.598–2.881)

Sun, G. Q.

37

39

1.055 (0.653–1.705)

69

73

1.058 (0.727–1.538)

190

215

0.934 (0.672–1.298)

Tong, Z. C.

179

180

1.089 (0.03–1.477)

110

121

0.926 (0.673–1.274)

37

43

0.887 (0.555–1.417)

Wang, K

176

192

0.852 (0.645–1.124)

187

181

1.062 (0.805–1.402)

39

29

1.382 (0.837–2.283)