Skip to main content

Table 4 Correlation coefficient and significance levels for XRCC5 (0R/1R/2R/3R), XRCC6 (C/G) and XRCC7 (G/T) at different biological end points

From: Radio-adaptive response and correlation of non-homologous end joining repair gene polymorphisms [XRRC5 (3R/2R/1R/0R), XRCC6(C/G) and XRCC7 (G/T)] in human peripheral blood mononuclear cells exposed to gamma radiation

Gene name ADNA damage at different doses BmRNA expression at 4 h post-irradiation with different doses CDNA repair at different post-irradiation time points DmRNA expression at various post-irradiation time points
r P r P r P r P
XRCC5 (0R/1R/2R/3R)
0R/0R 0.971** 0.001 −0.339 0.512 −0.939* 0.018 −0.979** 0.004
0R/2R 0.986** 0.0001 0.846* 0.034 −0.900* 0.038 0.737* 0.019
1R/1R 0.947** 0.0001 0.464** 0.001 −0.859** 0.0001 0.366* 0.020
1R/2R 0.967** 0.0001 0.698** 0.0001 −0.879** 0.0001 0.562** 0.001
2R/2R 0.916** 0.0001 0.831** 0.0001 −0.906** 0.0001 0.871** 0.0001
XRCC6 (C/G)
CC 0.940** 0.0001 0.486** 0.0001 −0.892** 0.0001 0.364** 0.009
CG 0.946** 0.0001 0.631** 0.0001 −0.859** 0.0001 0.433** 0.005
GG 0.970** 0.0001 −0.463 0.129 −0.879** 0.001 −0.581 0.078
XRCC7 (G/T)
GG 0.963** 0.0001 0.086 0.650 −0.892** 0.0001 0.199* 0.048
GT 0.947** 0.0001 −0.020 0.879 −0.868 0.0001 0.100 0.489
TT 0.954** 0.0001 −0.376* 0.041 −0.878** 0.0001 −0.290* 0.020
  1. Correlation coefficient and significance levels at XRCC5 (0R/1R/2R/3R), XRCC6 (C/G) and XRCC7 (G/T) polymorphism. A. DNA damage at different dose groups, B. mRNA expression at 4 h post-irradiation, C. DNA repair at different post-irradiation time points D. mRNA expression at various post-irradiation time. (**) and (*) indicates sigificant correlation (P < 0.01) and (P < 0.05) respectively