Fig. 2From: Weight of evidence approach using a TK gene mutation assay with human TK6 cells for follow-up of positive results in Ames tests: a collaborative study by MMS/JEMSDifferentially expressed proteins (DEP) identified in TK6 cells exposed to 4-nitroanthranilic acid. a A total of 1078 DEPs that differentially expressed compared to control groups were identified based on a log2 fold change of ≥2. Effects of treatment time are greater than that of dose. b A total of 168 specific DEPs that differentially expressed compared to other groups were further extracted from the 420 DEPs in 24 h 800 μg/mL group based on a log2 fold change of ≥1Back to article page