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Table 3 Genotype distribution and allele frequencies of four SNPs in case and control group

From: Transcription factor 7-like 2 gene- smoking interaction on the risk of diabetic nephropathy in Chinese Han population

SNPs Genotypes and alleles Frequencies N (%) OR (95 %CI) * P-values
Control (n = 720) Case (n = 358)
rs12255372      
  GG 419 (58.2) 191 (53.4) Ref  
  GT 260 (36.1) 140 (39.1) 1.23 (0.90–1.66)  
  TT 41 (5.7) 27 (7.5) 1.38 (0.81–1.97)  
  G 1098 (76.02 522 (72.9) Ref  
  T 342 (23.8) 194 (27.1) 1.26 (0.88–1.69)  
HWE test for controls    0.936
rs7903146      
  CC 469 (65.1) 185 (51.7) Ref  
  CT 218 (30.3) 139 (38.8) 1.59 (1.21–1.99)  
  TT 33 (4.6) 34 (9.5) 1.82 (1.27–2.43)  
  C 1156 (80.3) 509 (71.1) Ref  
  T 284 (19.7) 207 (28.9) 1.64 (1.24–2.06)  
HWE test for controls    0.240
rs11196205      
  GG 427 (59.3) 191 (53.4) Ref  
  GT 256 (35.6) 139 (38.8) 1.28 (0.83–1.76)  
  TT 37 (5.1) 28 (7.8) 1.42 (0.78–2.09)  
  G 1110 (77.1) 521 (72.8) Ref  
  T 330 (22.9) 195 (27.2) 1.30 (0.81–1.87)  
HWE test for controls    0.864
rs290487      
  TT 473 (65.7) 215 (60.1) Ref  
  TC 219 (30.4) 123 (34.4) 1.30 (0.96–1.67)  
  CC 28 (3.9) 20 (5.6) 1.46 (0.90–2.05)  
  T 1165 (80.9) 553 (77.2) Ref  
  C 275 (19.1) 163 (22.8) 1.33 (0.94–1.72)  
HWE test for controls    0.674
  1. *Adjusted for gender, age, BMI, smoking, alcohol drinking, FPG, duration of diabetes and hypertension