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Table 4 GMDR analysis on the best SNP–SNP and gene- current smoking interaction models

From: Transcription factor 7-like 2 gene- smoking interaction on the risk of diabetic nephropathy in Chinese Han population

Locus no. Best combination Cross-validation consistency Testing balanced accuracy p-values*
SNP- SNP interactions *    
2 (1, 3) 8/10 0.5451 0.3770
3 (1, 3, 2) 6/10 0.5577 0.3240
4 (1, 3, 2, 4) 7/10 0.4960 0.6241
Gene- current smoking interactions **    
2 (1, 5) 9/10 0.5985 0.0107
3 (1, 5, 3) 7/10 0.5622 0.3770
4 (1, 5, 3, 2) 6/10 0.5577 0.1719
5 (1, 5, 3, 2, 4) 7/10 0.5212 0.4258
  1. *Adjusted for gender, age, BMI, smoking, alcohol drinking, FPG, duration of diabetes and hypertension
  2. **Adjusted for gender, age, BMI, alcohol drinking, FPG, duration of diabetes and hypertension
  3. rs7903146, rs12255372, rs290487, rs11196205 and current smoking were symbolized as 1–5, respectively