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Table 6 MDR analysis of SNP-SNP interactions in FCRL gene

From: Fc receptor-like 1, 3, and 6 variants are associated with rheumatoid arthritis risk in the Chinese Han population

Model Training Bal. Acc. Testing Bal. Acc. CV Consistency Accuracy Sensitivity Specificity OR (95%CI) p
rs58240276 0.527 0.492 6/10 0.525 0.408 0.641 1.23 (0.96–1.59) 0.11
rs2050568,rs58240276 0.539 0.514 10/10 0.538 0.363 0.712 1.41 (1.08–1.83) 0.01*
rs2050568,rs2317230,rs58240276 0.545 0.490 10/10 0.541 0.391 0.692 1.44 (1.11–1.87) 0.0057*
  1. Abbreviation: MDR: multifactor dimensionality reduction; SNP: single nucleotide polymorphism; CV: cross-validation; OR: odds ratio; CI: confidence interval
  2. Note: p is calculated using χ2 test. All p-values in this study are two-tailed. Bold values mean statistical significance.*p < 0.05 indicates statistical significance