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Table 6 MDR analysis of SNP-SNP interactions in FCRL gene

From: Fc receptor-like 1, 3, and 6 variants are associated with rheumatoid arthritis risk in the Chinese Han population

Model

Training Bal. Acc.

Testing Bal. Acc.

CV Consistency

Accuracy

Sensitivity

Specificity

OR (95%CI)

p

rs58240276

0.527

0.492

6/10

0.525

0.408

0.641

1.23 (0.96–1.59)

0.11

rs2050568,rs58240276

0.539

0.514

10/10

0.538

0.363

0.712

1.41 (1.08–1.83)

0.01*

rs2050568,rs2317230,rs58240276

0.545

0.490

10/10

0.541

0.391

0.692

1.44 (1.11–1.87)

0.0057*

  1. Abbreviation: MDR: multifactor dimensionality reduction; SNP: single nucleotide polymorphism; CV: cross-validation; OR: odds ratio; CI: confidence interval
  2. Note: p is calculated using χ2 test. All p-values in this study are two-tailed. Bold values mean statistical significance.*p < 0.05 indicates statistical significance
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Genes and Environment

ISSN: 1880-7062

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