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Fig. 2 | Genes and Environment

Fig. 2

From: 1,3-Butadiene: a ubiquitous environmental mutagen and its associations with diseases

Fig. 2

The structures of the urinary BD biomarkers reported in the literature. MHBMA1, N-acetyl-S-[1-​(hydroxymethyl)​-​2-​propen-​1-​yl]​-L-cysteine; MHBMA2, N-acetyl-S-(2-hydroxy-3-buten-1-yl)-L-cysteine; trans- and cis-MHBMA3, trans- and cis-N-acetyl-S-(4-hydroxy-2-buten-1-yl)-L-cysteine; DHBMA, N-acetyl-S-(3,4-dihydroxybutyl)-L-cysteine; THBMA, N-acetyl-S-(2,3,4-trihydroxybutyl)-L-cysteine; bis-BDMA; 1,4-bis(N-acetyl-L-cystein-S-yl)butane-2,3-diol; NC1, 1,4-bis(N-acetyl-L-cystein-S-yl)-2-butanone; NAC, N-acetyl-L-cysteine; EB-GII, N7-[1-​(hydroxymethyl)​-​2-​propen-​1-​yl]guanine; bis-N7G-BD, 1,4-bis(gua-7-yl)-2,3-butanediol. MHBMA1 and MHBMA2 are collectively called monohydroxybutenyl mercapturic acid (MHBMA), and trans- and cis-MHBMA3 are similarly called MHBMA3.

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