Reactions of 3′,5′-di-O-acetyl-2′-deoxyguansoine and 3′,5′-di-O-acetyl-2′-deoxyadenosine to UV light in the presence of uric acid

Table 2 Characteristics of Products Formed by UV Irradiation of AcdAdo with Uric Acid

Products	t_R (min)	λ_max (nm)	m/z (negative)	ε_{245 nm} (M⁻¹ cm⁻¹)^a
7. Ade	16.5	260	134	8450
8. Fapy-AcdAdo (fast)	28.7	259	352	2860
9. Fapy-AcdAdo (slow)	29.3	259	352	2860
10. 5′,8-cyclo-AcdAdo (fast)	33.9	274	332	8930
11. 5′,8-cyclo-AcdAdo (slow)	34.6	274	332	6910
12. 5′-deoxy-5′,8-cyclo -AcdAdo	35.3	264	274	9560
13. 8-oxo-AcdAdo	38.6	212, 269	350	10,220

^aThe values of ε_{245 nm} were calculated from the reported ε values for the products of dAdo at λ_max and their UV spectra obtained in the present study [11]

ISSN: 1880-7062