|
Compounds
|
% tail DNA (%)
|
|---|
|
0.5 h
|
2 h
|
4 h
|
6 h
|
24 h
|
|---|
|
Saline
|
9.6 ± 4.8 (5.0)
|
13.4 ± 1.0 (8.3)
|
10.2 ± 1.3 (5.7)
|
9.8 ± 3.1 (3.2)
|
8.3 ± 1.7 (2.6)
|
|
1% EtBr
|
31.0 ± 3.0a (25.8)
|
28.1 ± 1.6a (22.6)
|
55.3 ± 1.4a (61.5)
|
41.0 ± 6.5a (40.4)
|
10.0 ± 4.0 (5.4)
|
|
3% MMS
|
66.2 ± 1.8a (70.8)
|
63.6 ± 4.4a (69.4)
|
47.1 ± 7.2a (48.9)
|
50.1 ± 2.8a (56.0)
|
40.1 ± 2.4a (38.1)
|
|
1% 4-NQO
|
55.2 ± 11.2a (58.3)
|
38.9 ± 7.8a (39.4)
|
35.9 ± 2.6a (36.0)
|
26.1 ± 2.6a (22.0)
|
18.7 ± 5.0a (14.5)
|
- Data are presented as the mean ± SD (n = 3). Parentheses indicate the median
- EtBr Ethidium bromide, MMS Methyl methanesulfonate, 4-NQO 4-nitroquinoline 1-oxide
- aSignificantly higher than the negative control group at 5% probability level (Student’s t-test, one-tailed)
