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Table 3 Apoptosis and mutation induced by aflatoxin B1 for 6 h in wild-type Drosophila (mwh/flr)

From: Mutation and apoptosis are well-coordinated for protecting against DNA damage-inducing toxicity in Drosophila

 

Aflatoxin B1 (nmol/dish)

 

0

50

100

500

Apoptosis (number of clusters stained with AO/disc)

Time after the treatment was stopped (h)

    

  0

28.6 ± 11.0

56.5 ± 25.3

52.6 ± 22.0

 87.2 ± 27.5

  6

54.8 ± 18.9

60.3 ± 28.3

83.3 ± 34.1

 94.4 ± 34.6

  12

78.7 ± 26.7

70.2 ± 15.6

77.3 ± 19.5

116.2 ± 29.7

  18

35.2 ± 12.8

46.8 ± 10.6

53.2 ± 12.9

103.0 ± 41.1

  24

41.3 ± 19.0

28.4 ± 10.3

53.8 ± 22.7

 59.1 ± 27.5

Mutation (number of total spots/wing)

 

0.49

0.84*

1.14*

1.92*

Survival (%)

 

100

101

102

99.1

  1. *P < 0.05, a significant difference from the control (without treatment)