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Table 2 Incidence and average size of lung nodules of the left lung lobe in mice

From: Chemo-preventive effects and antitumorigenic mechanisms of beer and nonalcoholic beer toward 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) - induced lung tumorigenesis in A/J mice

Group

Treatment NNK or saline +  diet

n

Average body weight (g) at 30 wks

% of mice with nodules

No. of nodules per mouse

Average size of nodules (mm)

Exp. 1

 I

NNK ip +  water

15

25.7 ±  1.83

93.3

2.13 ±  1.19

1.29 ±  0.25

 II

NNK ip +  GB

15

23.4  ± 1.59

66.7

0.93  ± 0.80*

1.14  ± 0.08**

 III

NNK ip + Beer

15

26.0 ±  2.68

46.7

0.73 ±  0.88*

1.19 ±  0.18

 IV

saline ip +  water

12

24.2  ± 4.09

0

0

0

 V

saline ip +  GB

10

23.8 ±  2.63

0

0

0

 VI

saline ip +  Beer

10

28.1  ± 2.60

0

0

0

Exp. 2

 VII

NNK ip +  water

15

25.3 ±  3.96

100

5.47 ±  1.60

1.44 ±  0.32

 VIII

NNK ip +  NAB (A)

15

26.7  ± 3.40

86.7

3.00 ±  2.36#

1.42  ± 0.28

 IX

NNK ip +  NAB (B)

15

26.4 ±  2.44

80.0

1.67  ± 1.40#

1.41 ±  0.27

 X

saline ip +  water

10

32.4  ± 3.12

0

0

0

 XI

saline ip +  NAB (A)

10

31.7 ±  2.81

0

0

0

 XII

saline ip +  NAB (B)

10

31.3  ± 1.62

0

0

0

  1. *P < 0.005, significantly different from Group I
  2. **P < 0.05, significantly different from Group I
  3. #P < 0.005, significantly different from Group VII