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Table 1 Level of DNA damage of Laevifolin A treated HT-29 cells

From: Genoprotective potential of Macaranga species phytochemical compounds on HT-29 human colorectal adenocarcinoma cell line

Treatment

Level of DNA damage (Arbitrary unit)

Tail moment

% tail DNA

Negative control

0.25 ± 0.1

3.5 ± 1.1

30 min

0.53 ± 0.1

6.4 ± 1.6

1 h

0.45 ± 0.03

6.0 ± 0.6

4 h

0.31 ± 0.1

4.3 ± 1.2

24 h

0.69 ± 0.1

7.8 ± 0.7

Positive control (1 mM H2O2 for 30 min)

*14.91 ± 1.5

*22.6 ± 1.0

  1. The results are expressed as mean ± SE of three independent experiments
  2. *p < 0.05 versus negative control