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Table 2 Level of DNA damage of Menadione on pre-treated Laevifolin A HT-29 cells

From: Genoprotective potential of Macaranga species phytochemical compounds on HT-29 human colorectal adenocarcinoma cell line

Treatment

Level of DNA damage (Arbitrary unit)

Tail moment

% tail DNA

Negative control

0.26 ± 0.1

3.1 ± 0.4

Menadione

*7.00 ± 0.8

*23.4 ± 3.1

Laevifolin A + Menadione

*,#1.24 ± 0.1

*,#9.8 ± 0.9

Positive control (1 mM H2O2 for 30 min)

*,#20.92 ± 4.5

*,#39.8 ± 2.0

  1. The results are expressed as means ± SE of three separate experiments 
  2. *p < 0.05 versus negative control
  3. #p < 0.05 vs menadione