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Fig. 3 | Genes and Environment

Fig. 3

From: LncRNA PVT1 induces apoptosis and inflammatory response of bronchial epithelial cells by regulating miR-30b-5p/BCL2L11 axis in COPD

Fig. 3

miR-30b-5p targets BCL2L11. A TargetScan database predicts the binding site between miR-30b-5p and BCL2L11. B Luciferase reporter assay for elucidating the interaction between miR-30b-5p and BCL2L11. CD RT-qPCR and western blotting for detecting BCL2L11 mRNA (C) and protein expression (D) in 16HBE cells with or without CSE exposure. EF. RT-qPCR and western blotting for analyzing BCL2L11 mRNA (E) and protein expression (F) in 16HBE cells with PVT1 knockdown or miR-30b-5p overexpression. **p<0.01

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