Table 1 Formation of εGua in ss- and ds-DNA [Mean ± SD (ng/mL)]

Formation of ethenoGua in DNA by 6-oxo-compounds

 6-oxo-2,4-hepadienal

0.65 ± 0.02

^a8.40 ± 0.04

12.9

 6-oxo-2,4-decadienal

0.44 ± 0.01

2.64 ± 0.03

6.0

Formation of ethenoGua in DNA by 6-hydroxy-compounds

 6-OH-2,4-hepadienal

1.39 ± 0.05

^b4.12 ± 0.09

3.0

 6-OH-2,4-decadienal

2.17 ± 0.05

0.97 ± 0.04

0.45