Risk assessment of aflatoxin B1 in herbal medicines and plant food supplements marketed in Malaysia using margin of exposure and RISK21 approaches

Table 3 Estimated exposure, cancer risk and percentage cancer incidence attributed to aflatoxins for the general adult population

Exposure (ng/kg bw/ day)^a (ng/kg b.w./day)		Estimated cancer risk^b (no. of cancers/100,000 population/year)		% Cancer incidence^c attributable to AFB1 Exposure
Lower Boundary	Upper Boundary	Lower Boundary	Upper Boundary	Lower Boundary	Upper Boundary
0.006	10.456	0.000	0.261	0.002	4.149

^aBased on the mean body weight of the general adult population of 60 kg; ^bCalculated based on general adult population potency estimate of 0.025 cancers/100,000 population/year per ng/kg b.w./day; ^cBased on age-standardized incidence rate for liver cancer of 4.9/100,000 population/year [29]

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